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Treating obesity with behavior change, generic anti-obesity medications, and GLP-1 seems to reduce the risk profile associated with all of these [cardiometabolic] diseases, Frank added

However, their wealth of pleiotropic actions soon raised expectations that they might confer benefits on non-metabolic disorders
The total number of GLP-1-prescribing providers increased by 228% from July 2020 to May 2023

Median liver stiffness, a noninvasive marker of fibrosis, declined from 3.4 to 3.1 kPa at week 12 ( p = 0.049), as assessed by magnetic resonance elastography (MRE)
