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Thus, vitamin D and/or VDR deficiency might play an important role in the pathogenicity of IBS owing to their role in intestinal barrier functions and low-grade mucosal inflammations
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doi:10.1016/j.jacbts.2022.12.011 Collins L, Costello RA
9.1 Criteria suggesting failed pharmacology rather than failed biology Several characteristics consistently indicate that a peptide system may have been abandoned prematurely due to pharmacologic or methodological limitations rather than biological inadequacy
