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thus, there is a smaller window for weight loss, as body weight defence mechanisms have a greater role in lean mice, potentially confounding the absence of treatment effects

doi: 10.1056/NEJMoa1212914 [DOI] [PMC free article] [PubMed] [Google Scholar] 242

Toxicological studies of cyclodextrin effects on the nasal mucosa confirm that dimethyl-beta-cyclodextrin and randomly methylated beta-cyclodextrin are considered safe for nasal use at therapeutic concentrations
