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( 10.2337/db11-1073) [DOI] [PMC free article] [PubMed] [Google Scholar] Chang-Chretien K Chew JT & Judge DP

Its simultaneous activation of three receptor pathways GLP-1R for appetite suppression and insulin secretion, GIPR for augmented insulin response and central appetite modulation, and GCGR for energy expenditure and hepatic fat mobilisation produces metabolic effects that exceed what single or dual agonism can achieve [4][8][9]

2013;30:e1858

Working with a registered dietitian and psychologist can help: Fuel your body with confidence Rebuild trust with hunger and fullness cues Address body image concerns Develop skills for emotional regulation Heal from trauma and internalized weight bias Receive help for mental health concerns