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When the thyroid gland is removed, the result is a state of hypothyroidism, and the patient will require lifelong thyroid hormone replacement therapy

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Al-SadawiMAAslamFMTaoMAlsaiqaliMAlmasryIOFanRet alEffects of GLP-1 agonists on mortality and arrhythmias in patients with type II diabetes

And when side effects persist beyond the typical 4-6 week adjustment period, switching to an alternative with a different receptor binding profile or mechanism of action often resolves the issue entirely