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tirzepatide downsides Comparative safety and side effects of semaglutide and tirzepatide: Implications for clinical decision-making in obesity management Tirzepatide Long-Term Side Effects: Safe
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This means that while mild to moderate IBS may not prevent Wegovy use, severe gastrointestinal symptoms might warrant caution

An optogenetic stimulation of GLP-1Rs in habenular circuits was also shown to abolish nicotine reward and decrease nicotine intake in mice 109
