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These findings suggest that neither direct release of GLP-1 in the OB from hindbrain PPG neuron projections, nor volume transmission via release of GLP-1 into the ventricles are likely sources of GLP-1 to activate OB GLP-1R
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The present studies demonstrate that semaglutide-induced weight loss can be divided into different stages based on the rate of weight loss, and these stages are characterized by different feeding behaviors and metabolic parameters
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