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reported that cleavage products derived from GLP-1 reduced tubulointerstitial renal damage, lowered the expression of tubular injury markers, and attenuated the renal accumulation of macrophages and T cells ( Glycemic Control Although the glucose-independent mechanisms are emphasized, glycemic control by GLP-1RAs is considered to be involved in its renoprotective effects

Metabolism (2005) 54(2):24754.10.1016/j.metabol.2004.08.020 111 BymasterFPFelderCCTzavaraENomikosGGCalligaroDOMckinzieDL

In patients using GLP-1 analogs, including adolescents, its essential to monitor kidney function

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