glp-1 obesity drug news today october 16 2025 What's next for innovation: A primer on the race reshaping pharma and chronic disease care GLP-1 therapies are changing obesity
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doi:10.1371/journal.pone.0187836 225
Avogaro A, Fadini GP

GLP-1 dose conversion chart and safe switching guide Navigating GLP-1 agonist conversions requires more than a simple chart
The presence of GLP-1 receptors in testicular tissue and evidence of direct, weight-loss-independent effects on sperm function raises the possibility that GLP-1 drugs may act on male reproductive biology through two distinct mechanisms simultaneously: one systemic (through metabolic improvement) and one local (through direct testicular signaling)