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All experiments undertaken were approved by the University of Ottawa Animal Care Committee (AUP 2909 and 4379)

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Here, it is, however, important to note that the desensitization of the GIPR is different from that of the GLP-1R, as GIPR internalization relies on arrestins [559], while that is not the case for the GLP-1R [558]

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Semaglutide and statins work through different biological pathways and do not interfere with each other's effectiveness

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Injection-site irritation is another possible skin-related side effect of Wegovy injections

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