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It's also important to be aware of serious conditions that require urgent evaluation regardless of medication expiration status, including severe abdominal pain radiating to the back (possible pancreatitis) or persistent right upper quadrant pain, fever, or jaundice (possible gallbladder disease)both known risks with GLP-1 receptor agonists

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Cureus 15 (8), e43697

This approach enables a broad exploration of mechanisms and clinical implications, but it also introduces the potential for selection bias