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The modification causes it to bind to albumin, protecting it from metabolic degradation and decreasing its renal clearance, thus prolonging its half-life

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doi: 10.1016/j.molmet.2018.12.001 [DOI] [PMC free article] [PubMed] [Google Scholar] 42.Adriaenssens AE, Biggs EK, Darwish T, et al