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Dula also significantly reduced the expression of transforming growth factor-1 (TGF-1), phosphatidylinositol-3-kinase (PI3K), protein kinase B (AKT) signaling pathway, and the inflammatory cytokines: nuclear factor kappa B (NF-B), interleukin-6 (IL-6), and interferon- (IFN-) in colonic cellular structures
Retatrutide is suitable for research teams examining integrated metabolic signaling pathways and multi-receptor peptide interactions within controlled experimental models

Propensity score matching (PSM) with 1:1 ratio was employed to create balanced cohorts