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This dehydration risk is the primary concern prompting temporary metformin discontinuation
The World Health Organization's December 2025 guidelines emphasized the importance of resistance training to protect muscle mass during GLP-1 therapy, acknowledging this as a limitation of current treatment approaches [49]
Important side effects that warrant immediate attention by a doctor include persistent vomiting, diarrhea and/or abdominal pain
TRIUMPH-1 Phase 3 topline results, 21 May 2026
