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Description
For someone who wants steady improvements and has tolerated GLP-1 receptor agonists before, Ozempic is a well-understood choice
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Cold insulin is more painful to inject

However, an anabolizing agent such as GLP1-RAs can also upregulate the AMPK-pathway, due to cAMP accumulation ( Figure 1 )

Nausea, vomiting, and other gastrointestinal symptoms are common, particularly when starting or increasing the dose and in T1D trials, these rates were similar to those seen in T2D and obesity trials