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In some integrated care systems, GPs with enhanced diabetes training may initiate GLP-1 therapy directly, supported by local prescribing protocols
Some insurance plans cover Ozempic for type 2 diabetes or Wegovy for obesity with appropriate prior authorization

In additional analyses, we estimated hazard ratios for the following time periods after the start of treatment: days 1-365, days 366, and days 731
The SURPASS-CVOT trial (NCT04255433) will assess the cardiovascular safety of tirzepatide compared to dulaglutide in people with T2D and established atherosclerotic disease [111]
