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2012 Jan;38(1):104-10

The difference between the lowest and highest of those numbers is tenfold

Favourable changes in cardiometabolic markers were also reported in the Phase 2 trial data, including reductions in: Systolic blood pressure Triglyceride levels Waist circumference (a proxy for visceral adiposity) However, these are surrogate markers and should not be interpreted as evidence of a reduction in major adverse cardiovascular events (MACE)

Table 2 presents the data, findings, and conclusions of these meta-analyses
