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Regarding renal outcomes, the combination therapy showed a reduction in events that did not reach statistical significance when compared to SGLT-2i monotherapy
Compared with healthy cartilage, degenerated cartilage shows lower GLP-1 receptor expression ( Analgesic effects Body weight Two studies investigated the effects of GLP-1 RAs on body weight in murine models of osteoarthritis, yet reported contradictory findings

doi: 10.1001/jama.2023.24945 32

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