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Inflammation has been implicated in the pathophysiology of type 2 diabetes (Eguchi and Nagai, 2017)

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The SURPASS-3 study was set up to investigate the efficacy and safety of tirzepatide versus a titration of the basal insulin degludec inadequately controlled by an oral therapy of T2D by metformin with or without an SGLT2 inhibitor comedication for 52 weeks (72)
