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doi:10.1186/s10194-022-01402-2

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While neither tirzepatide nor niacinamide requires routine dose adjustment for hepatic impairment, patients with severe liver disease should be monitored closely if treatment is deemed necessary by the prescribing provider

These products may come in versions that differ from the brand-name companies, such as vials of powder that must be dissolved in liquid, or as tablets or nasal sprays