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Description
Normal Volume With Low Serum Sodium In euvolemic hyponatremia: Total body sodium is typically normal Excess water retention slightly expands extracellular volume Sodium concentration falls due to dilution rather than loss Patients often lack overt signs of volume depletion or fluid overload, making this classification more challenging to identify clinically
Main mechanism Inhibits the reuptake of dopamine, norepinephrine, and serotonin in the brain (a triple monoamine reuptake inhibitor, or SNDRI)

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Moreover, mutation-specific therapeutic targets, beyond the current focus on CYP11B2 inhibition, also present promising avenues for tailored interventions
