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There is no substantial evidence that it increases weight loss beyond that resulting from caloric restriction, that it causes a more attractive or normal distribution of fat, or that it decreases the hunger and discomfort associated with calorie-restricted diets. Its proponents will state that hCG enhances compliance as it reduces side effects of VLCD and increases the patients basal metabolic rate

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Deviating from this schedule has no peer-reviewed evidence supporting safety or efficacy

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"FDA approves Novo Nordisk's oral semaglutide for cardiovascular (CV) risk reduction in adults with type 2 diabetes who are at high risk, including those who have not had a prior CV event" (Press release)

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Wegovy is a GLP-1 agonist, a class of obesity drugs promising a sea change in weight loss

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