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doi: 10.1016/0014-5793(81)80288-8 19 LundPKGoodmanRHDeePCHabenerJF
A notable study, the BRAVES trial, demonstrated histological improvement in MASH without worsening of fibrosis in 55 % of patients undergoing Roux-en-Y gastric bypass or sleeve gastrectomy after one year, compared to only 15 % in patients who undertook lifestyle modification alone [202]
Gradual dose reduction may help stabilize appetite signals during the transition
