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Knapen (86) also reported through follow-up studies that the pancreatic tumor risk in patients treated with GLP-1RA for a long period of time was not significantly different

Rats receiving vagotomy do not reduce food intake in response to peripherally injected GLP-1 indicating that vagal afferent nerves are needed to relay peripheral GLP-1 signals to higher brain regions to regulate feeding (Abbott et al., 2011)

A phase IIa trial of metformin for colorectal cancer risk reduction among individuals with history of colorectal adenomas and elevated body mass index

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