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Corticotropin-releasing hormone and the sympathoadrenal system are major mediators in the effects of peripherally administered Exendin-4 on the Hypothalamic-Pituitary-Adrenal axis of male rats

Glucagon-like Peptide-1 (GLP-1, 3031 aa) is a natural gastrointestinal incretin hormone of the glucagon peptide family, secreted from the enteroendocrine L-cells in the distal gut to stimulate insulin secretion in response to postprandial hyperglycemia (Figure 1)

Dehydration affects muscle function and may precipitate cramping
