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Description
These preclinical findings support the further development and advancement of these small molecules as potential therapies for type 2 diabetes and obesity
In the published data to date, hypersensitivity with retatrutide has mainly taken the form of non-severe skin conditions such as rash, itching (pruritus), and urticaria (hives)
These results suggest that the any potential associations between GLP-1RAs and intestinal obstruction in patients with T2DM may not entirely mediate through weight loss
doi: 10.1038/nm.4345
