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Description
Semaglutide versus placebo in people with obesityrelated heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF DM randomised trials

Clinical trials show average weight loss of 15 to 20% of body weight over 12 to 18 months, with some people losing more
Clinical data suggests an average of two to four pounds lost in the first four weeks at starting doses, with considerable variation based on individual baseline metabolism and activity levels

No nausea, steady weight loss, I felt energetic