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Moreover, we found that the expression of GLP-1 signaling-related genes ITPR1 and ADCY5 were significantly reduced in CRC tissues, and GLP-1 receptor agonist semaglutide impaired the migration capacity of CRC cells, indicating its protective role

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These data indicated that the status of cell in pancreas and intestine is maintained and the molecular expression level of cell dysfunction is increased after treatment

doi: 10.1038/nmeth.3337
