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In addition, in the EMPEROR-reduced trial, enrolling about 3700 patients affected by heart failure with reduced ejection fraction (HFrEF), empagliflozin significantly reduced the risk of heart failure hospitalization and decreased total hospitalization for HF regardless of the presence of diabetes or baseline levels of glycohemoglobin (HbA1c) (49, 50)

Quality assessment was performed using the Cochrane risk-of-bias tool

Learn More Metformin A medication indicated for the treatment of Type 2 Diabetes, which may also be prescribed for weight loss if deemed appropriate by a healthcare provider

GLP-1 receptor agonists have shown the ability to reduce neuroinflammation and oxidative stresswell-recognized contributors to Alzheimers diseaseand provide neurotrophic effects in animal models of Alzheimers, the authors write, while cautioning that this needs to be verified by further clinical trials