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We do know that GLP-1s have powerful anti-inflammatory effects, but we dont yet fully understand: Long-term impact on Lipedema fat Effect on fibrosis Impact on lymphatic health Interaction with Lipedema-specific metabolic patterns For now, the approach must be personalised, cautious, and monitored

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Prioritize mood stabilizers and second-generation antipsychotics (SGAs) in the management of BD-I depression and use adjunctive antidepressants as a second-line treatment option