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They might recommend starting with a lower dose of semaglutide and gradually increasing it

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In some animal experiments, it has been reported that GLP-1 may be effective in improving inflammation [27,28], postprandial hyperlipidemia [29,30], endothelial cell dysfunction [31], and oxidative stress [32], as well as protecting -cells [33,34]
Rather than following a fixed rule, monitor urine color as a practical hydration indicatorpale yellow suggests adequate hydration, while dark yellow or amber indicates insufficient fluid intake