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Media and Commercial Contact Matthew Hanson [email protected] SOURCE Black Buffalo

These changes include: Reduction of beneficial bacteria, Bifidobacterium Reduction of beneficial short-chain fatty acids (a main energy source for the gut cells) Elevated pH in the gut can allow for less beneficial bacteria to grow, leading to dysbiosis

Without clarity on what is required or how it will be assessed, applicants have been driven to maximalist interpretations of the guidance, leading to costly and lengthy applications and diverting scientific and engineering resources away from innovation and into compliance with opaque regulatory demands