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The protamination of sperm chromatin facilitates compaction of the nucleus, protecting the paternal genome during its passage and delivery to the oocyte

In addition, genes upregulated by smoking among apical epithelial cell types ( KRT8 high , mucus secretory, and ciliated) were enriched for mucus secretory cell markers, supporting an increase in the secretory activity of these cells (Fig

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Nicotine and other chemicals in cigarettes and smoking can cause diabetes by disrupting insulin production and action, making it harder to control blood sugar levels