smoking cigarettes and ed E-Cigarettes May Be Independently Linked to Erectile Dysfunction, New Research Finds EP233: Ending vaping and smoking
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The central nicotinic cholinergic receptors, namely the low affinity 7 and the high affinity 42 nicotinic receptors located in the ventral tegmental area (VTA), are stimulated by nicotine resulting in a rapid release of dopamine in the nucleus accumbens, mediating the rewarding and reinforcing effects of nicotine (25) (Figure 1)

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