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A causal association between serum cotinine and kidney stones in MR A total of 10 SNPs were eventually selected after a series of rigorous screenings, the details of which are shown in Supplementary Table S5

Most cross-species findings appeared to be buried under the genomic significance thresholddemonstrating the strength of our partitioned heritability approach, which captures genes with small effect sizes peppered across the genome

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While it may reduce exposure to some of the toxic substances found in traditional cigarettes, it still delivers nicotine and other chemical compounds that can affect multiple systems in the body over time