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Description
INH is a prodrug that enters the Mtb cytoplasm via passive diffusion, where it inhibits mycolic acid synthesis by targeting the InhA enzyme, an essential catalyst in an early step of the mycolic acid biosynthetic pathway (Mitchison, 1956)
SHS exposure is associated with increased incidence and severity of respiratory tract infections, such as respiratory syncytial virus (RSV) infection in neonates or pneumonia in younger children [9]
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