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6.4 Racial and Ethnic Differences Racial differences in nicotine and cotinine metabolism have been observed

As for the seizure risk, its possible that more investigation will find theres actually no link, and that theres some other factor that explains the cases already reported

And will it help Philip Morris with its goal to replace cigarettes with non-combustible alternatives

Protecting access to harm-reducing vapor products is connected to excise tax design as nicotine-containing products are substitute goods.[73] By looking at cessation behaviors in the context of a tax increase on vapor products, a recent publication found that 32,400 smokers in Minnesota were deterred from quitting cigarettes after the state implemented a 95 percent excise tax on vapor products.[74] The substitution effect is also evident looking at the smoking rates in the U.S