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These include tar, carbon monoxide, acetone, and nicotine

Here's a nice video that summarizes how carcinogenic effects of cigarettes can lead to heart disease and lung diseases: Smoking and Septoplasty: A Risky Combination Smoking is a well-known risk factor in surgery and wound healing due to the harmful effects of nicotine and other toxins present in tobacco smoke
Transmission electron microscopic findings of the ET Tissues were harvested in the same manner as described above
