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Evidence-based and cost-effective strategies for reducing the burden of tobacco are available [8, 9]
Tobacco burning creates tar, a mixture of hazardous substances, including polycyclic aromatic hydrocarbons (PAHs), heavy metals, and free radicals, which raise the risk of developing stroke by inducing vascular endothelial cell damage and lowering nitric oxide generation while increasing oxidative stress
Countries that included at least one question about awareness(69/75), ever use (54/75) and current use(67/75) e-cigarettes were included in the analyses
high expression of MMP-9 and HMGB-1 also plays a role in TAO-related vascular lesions (136, 137)
