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There's another factor here aside from cardiovascular risk that suggests hormonal birth control isn't right for smokers: Research from three large clinical trials found that smokers taking the pill were more likely to experience spotting or bleeding than non-smokers, suggesting that nicotine might influence the way the body breaks down estrogen

[] [DOI] [PMC free article] [PubMed] [Google Scholar] West R, Baker CL, Cappelleri JC, Bushmakin AG

adults who smoke daily had their first cigarette by the age of 21
