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Policy and research implications Our findings on how reduced harm perceptions, the packaging, price and indoor use of IQOS influenced use have important policy and research implications

[122] The findings are a comparison between e-cigarette daily usage and the regulatory limits of chronic Permissible Daily Exposure from inhalation medications outlined by the US Pharmacopeia for cadmium, chromium, copper, lead and nickel, the Minimal Risk Level outlined by the Agency for Toxic Substances and Disease Registry for manganese and the Recommended Exposure Limit outlined by the National Institute for Occupational Safety and Health for aluminum, barium, iron, tin, titanium, zinc and zirconium, [107] referring to a daily inhalation volume of 20 m 3 air and a 10-h volume of 8.3 m 3

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Even among current smokers who are interested in using IQOS to help them quit, public health benefit hinges on whether quit intentions translate into actual smoking cessation over time