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As the local regulatory effort spread across the country and more cigarette vending machines ended up either in dumps or as collector items in basement rec rooms, the focus switched in the mid-1990s to restrictions on self-service displays, especially in retail stores that allowed minors to be present

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23 Nicotine and Vascular Reactivity Both vascular endothelial cells (EC) and vascular smooth muscle cells (VSMC) express multiple and subunits of nAChR, 2428 rendering the vasculature a direct target of nicotine