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Tobacco and cancer of the digestive system Smoking tobacco is a major risk factor for developing mouth, lip, and larynx cancer, as well as cancer of the esophagus, stomach, pancreas, liver, colon, and rectum
In the United States alone, cigarettes and other tobacco products are responsible for more than 480,000 deaths annually
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These immune checkpoints may contribute to the maintenance of physiological health (50, 53)
