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In medical science, the gold standard for determining cause-and-effect relationships is a randomized controlled clinical trial, in which participants are randomly assigned and doses are regulated

In the United States, it is projected three million fractures occur annually due to osteoporosis, with an estimated economic cost of $25.3 billion by 2025 [3]
Chan Kwong AH-XP, Calvier EAM, Fabre D, Gattacceca F, Khier S

Some have also mulled the idea of changing the legal smoking age, with the U.K
