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A 2004 series of monographs released by the International Agency for Research on Cancer (IARC), a part of the World Health Organisation (WHO), summarized research from the 1960s onwards about the carcinogenicity of tobacco on various laboratory animals

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Simulated environmental tobacco smoke [edit] To study the consequences of passive smoking, scientists expose animals to sidestream smoke, that which emanates from the cigarette's burning cone and through its paper, or a combination of mainstream and sidestream smoke