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With abstinence from alcohol, brain perfusion abnormalities may recover, but there are several factors that may influence recovery, such as age, diet, exercise, genetic predispositions and the topic of our research other substances such as tobacco products. Cerebral Perfusion in Smokers and Non-Smokers The researchers measured cerebral perfusion in 19 non-smoking alcohol-dependent patients, 22 smoking alcohol-dependent patients, and 28 age-matched, non-smoking, light-drinking controls