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Patients with CHD are also at risk of developing atherosclerotic cardiovascular disease

Bladder cancer caused by smoking develops through a complex biological process driven by the harmful chemicals found in tobacco smoke

Some notable C&D blends that feature dark-fired tobacco include Burley Flake #5, Redburn, and Dreams of Kadath with each one offering their own distinct flavor profile and highlighting dark-fired tobacco's versatility

Presumably, given the size of the Durham auction market, Reynolds wanted a presence convenient to the auction warehouses to press and store tobacco for shipping to their factories