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[1] Smoking and Tobacco Use: Current Cigarette Smoking Among Adults in the United States, U.S

2015;39(5): 477to84 Monitor the UV index and protect your skin this spring

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Polycyclic aromatic hydrocarbons contained in Cigarette smoke increase the activity of CYP 1A2 enzymes, and thus affects the metabolism of its substrates, several antipsychotics, e.g., olanzapine, haloperidol, clozapine, as well as some antidepressants (amitriptyline, clomipramine, doxepin, duloxetine, fluvoxamine, imipramine, mianserin, mirtazapine) and benzodiazepines (64)