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Top view (left), side view (middle), front view (right)

Australia enforces strict regulations on packaging, nicotine content disclosure, retail licensing, advertising restrictions, and age verification requirements

To identify which immune cell type(s) in the tumor environment were affected by nicotine and contributed to differential outgrowth of primary and metastatic tumors, we examined the composition of neutrophil (ELA2), macrophage (F4/80), and NK (NKp46) cells in primary and metastatic tumors of control and nicotine-treated mice by immunohistochemical (IHC) analysis (Fig

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