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Tobacco products like chewing tobacco fall under strict guidelines, so lets break it all down

Furthermore, studies using diet-induced models of MASLD have shown that e-cigarette exposure exacerbates preexisting liver injury, worsening steatohepatitis through amplified oxidative stress, mitochondrial dysfunction, and inflammatory responses [134]

"Certainly large pharmaceutical companies with interests in stop-smoking medicines provide very substantial financial support to some of the public health groups that are calling for e-cigarettes to be banned." Source : An Interview with Adrian Payne On Falling in Love With E-Cigarettes 34